A hotel manager overcomes her fear of flying and boards a busy late-night flight to Miami, seating herself next to the seemingly friendly man she met in the airport. However, once the plane leaves the ground, she discovers her fellow passenger is a terrorist intent on involving her in an assassination plot. Wes Craven's suspense thriller, starring Rachel McAdams, Cillian Murphy and Brian Cox.

An overnight flight to Miami quickly becomes a battle for survival when Lisa realizes her seatmate plans to use her as part of a chilling assassination plot against the Deputy Secretary of Homeland Security. If she refuses to cooperate, her own father will be killed. As the miles tick by, she's in a race against time to find a way to warn the potential victims before it's too late.