Vampire warrior Selene returns to life after spending years in cryonic suspension by a scientist. Escaping from the facility where she is being held, she finds humans have discovered the existence of the undead and are planning to wipe them out, a new breed of mutant werewolves has emerged, and her super-powered daughter holds the key to ending the conflict. Action fantasy, with Kate Beckinsale, India Eisley and Stephen Rea.

Having escaped years of imprisonment, vampire warrioress Selene finds herself in a changed world where humans have discovered the existence of both Vampire and Lycan clans and are conducting an all-out war to eradicate both immortal species. Now Selene must battle the humans and a frightening new breed of super Lycans to ensure the death dealers' survival.