Three intertwined tales chronicling aspects of America's war on drugs. A controversial judge makes a shocking discovery after being appointed to spearhead the campaign, two policemen in Mexico pull out all the stops to halt a cocaine shipment, and the wife of a jailed mobster resolves to regain control of his crumbling empire. Steven Soderbergh's crime drama, starring Michael Douglas, Catherine Zeta-Jones, Benicio Del Toro, Dennis Quaid, Don Cheadle and Miguel Ferrer.

An exploration of the United States of America's war on drugs from multiple perspectives. For the new head of the Office of National Drug Control Policy, the war becomes personal when he discovers his well-educated daughter is abusing cocaine within their comfortable suburban home. In Mexico, a flawed, but noble policeman agrees to testify against a powerful general in league with a cartel, and in San Diego, a drug kingpin's sheltered trophy wife must learn her husband's ruthless business after he is arrested, endangering her luxurious lifestyle.