Writer Mark has survived polio, but still needs to use an iron lung. At the age of 38, he has begun a writing career but has never had sex. With the support of his parish priest, he enlists the help of a sex therapist in gaining the confidence to lose his virginity. Comedy drama, starring John Hawkes, Helen Hunt and William H Macy.

Though a childhood bout with polio left him dependent on an iron lung, Mark O'Brien maintains a career as a journalist and poet. A writing assignment dealing with sex and the disabled piques Mark's curiosity, and he decides to investigate the possibility of experiencing sex himself. When his overtures toward a caregiver scare her away, he books an appointment with sex surrogate Cheryl Cohen-Greene to lose his virginity.