A doctor in 1980s New York treats some of the first people in America to be diagnosed with Aids, while a gay rights activist investigates the new disease that people around him are dying from. However, they both face opposition from medical authorities, which refuse to recognise the danger. Fact-based drama, with Mark Ruffalo and Julia Roberts.

The story of the onset of the HIV-AIDS crisis in New York City in the early 1980s, taking an unflinching look at the nation's sexual politics as gay activists and their allies in the medical community fight to expose the truth about the burgeoning epidemic to a city and nation in denial.