A US Cavalry colonel is ordered to escort a trainload of whisky to Denver. Prepared for a straightforward job, he little realises the trouble his cargo will cause, as a gang of temperance ladies and a rascally Sioux tribe try to get their hands on the shipment for very different reasons. Comedy Western, starring Burt Lancaster, Lee Remick, Jim Hutton, Donald Pleasence and Martin Landau.

A wagon train heads for Denver with a cargo of whisky for the miners. Chaos ensues as the Temperance League, the US cavalry, the miners and the local Indians all try to take control of the valuable cargo.