A scientist desperately tries to find a cure for his dying wife, while in the 16th-century a conquistador battles to locate the fountain of youth for his queen and in the far future, an explorer searches for eternal life in the depths of space. Darren Aronofsky's romantic sci-fi drama, starring Hugh Jackman and Rachel Weisz in multiple roles, alongside Ellen Burstyn and Mark Margolis.

Spanning over one thousand years, and three parallel stories, The Fountain is a story of love, death, spirituality, and the fragility of our existence in this world.