The detective investigates a series of seemingly unconnected crimes all around the world, and becomes convinced one man is behind them all - the elusive Professor Moriarty. He sets forth on an international journey to bring the evil mastermind to justice, but finds he is dealing with a foe who is his intellectual equal. Detective thriller sequel, starring Robert Downey Jr, Jude Law, Noomi Rapace and Rachel McAdams.

There is a new criminal mastermind at large (Professor Moriarty) and not only is he Holmes’ intellectual equal, but his capacity for evil and lack of conscience may give him an advantage over the detective.