Dim-witted Cindy Campbell gets a job as the caretaker of a haunted house, where she comes into contact with the ghost of a little Japanese boy. He tells her he knows a secret way to rid the Earth of invading aliens - but then he unfortunately vanishes before passing it on to her. Spoof horror sequel, starring Anna Faris, Leslie Nielsen, Craig Bierko, Anthony Anderson and Carmen Electra.

Cindy finds out the house she lives in is haunted by a little boy and goes on a quest to find out who killed him and why. Also, Alien "Tr-iPods" are invading the world and she has to uncover the secret in order to stop them.