A pet chameleon with an active imagination ends up lost in the desert. He makes his way to a lawless town of animals, where he is mistaken for a deadly gunslinger and made sheriff. He organises the townsfolk into a posse when bandits led by an evil rattlesnake steal their supply of water. Animated comedy, with the voices of Johnny Depp, Isla Fisher and Bill Nighy.

When Rango, a lost family pet, accidentally winds up in the gritty, gun-slinging Western town of Dirt, the theater-loving lizard suddenly finds himself the newly appointed sheriff. Welcomed as the last hope the town has been waiting for, Rango is forced to play his new role to the hilt and uncover the truth behind a looming water crisis—before his act catches up with him.