Narcotics detectives Crockett and Tubbs go undercover and pose as smugglers to infiltrate a powerful drug cartel. However, the operation is threatened when Crockett becomes dangerously involved with the wife of the head of the organisation. Michael Mann's crime thriller based on the 1980s TV series, starring Colin Farrell, Jamie Foxx, Gong Li, Naomie Harris and Luis Tosar.

A case involving drug lords and murder in South Florida takes a personal turn for undercover detectives Sonny Crockett and Ricardo Tubbs. Unorthodox Crockett gets involved romantically with the Chinese-Cuban wife of a trafficker of arms and drugs, while Tubbs deals with an assault on those he loves.