An insurance investigator suffers from short-term memory loss after an attack in which his wife was also raped and murdered. Unable to remember events for more than a few minutes, he is determined to track down the killer and relies on copious note-taking and reminders tattooed on his body to aid his mission. Christopher Nolan's thriller, starring Guy Pearce, Carrie-Anne Moss, Joe Pantoliano and Mark Boone Jr.

Leonard Shelby is tracking down the man who raped and murdered his wife. The difficulty of locating his wife's killer, however, is compounded by the fact that he suffers from a rare, untreatable form of short-term memory loss. Although he can recall details of life before his accident, Leonard cannot remember what happened fifteen minutes ago, where he's going, or why.