This attempt to update Fantastic Voyage doesn't measure up to director Joe Dante's best work, but it's still a notch above the usual Hollywood fodder. Dennis Quaid plays the hotshot military man who's miniaturised and mistakenly pumped into the body of lowly supermarket clerk Martin Short. The effects are excellent and Dante's sly humour shines through occasionally, but it lacks the anarchy the director is noted for and Short's hysterics eventually begin to grate. Meg Ryan pops up as the love interest and there are good supporting turns from Kevin McCarthy and Henry Gibson. Dante regular Dick Miller, once a fixture in Roger Corman's movies, has a cameo as a cab driver.

Test pilot Tuck Pendleton volunteers to test a special vessel for a miniaturization experiment. Accidentally injected into a neurotic hypochondriac, Jack Putter, Tuck must convince Jack to find his ex-girlfriend, Lydia Maxwell, to help him extract Tuck and his ship and re-enlarge them before his oxygen runs out.