A detective investigates a series of murders and discovers they are the work of an evil spirit from the very beginnings of the human race. The entity was the first woman in the world, but was rejected in favour of Eve, and has sought revenge against her descendants ever since. Horror, with Ving Rhames and Ava Gaudet.

Set in present day Chicago, the ancient avenging demon Lilith, attempts to destroy a young paramedic's life while destroying anyone who interferes with her plan.