A mad doctor promises to remake his colleague's girlfriend from spare parts, but they are threatened by a vengeful professor they decapitated and brought back to life as an animated servered head. Horror sequel, loosely inspired by an HP Lovecraft story, starring Jeffrey Combs and Bruce Abbott.

Unperturbed by the disastrous outcome of his previous meddling with the dead, Dr. West continues his research into the phenomenon of re-animation; only this time, he plans to create life – starting with the heart of his young protégé Dan's dearly deceased Meg Halsey.