The sadistic supervisor of a lunatic asylum is enraged when a political reformer wants to put a stop to his cruelty, so has her branded insane and committed to the institution. She conspires with the patients to get revenge for the mistreatment they have suffered. Horror, starring Boris Karloff and Anna Lee.

London, 1761. St. Mary's of Bethlehem, a sinister madhouse, is visited by wealthy people who enjoy watching the patients confined there as if they were caged animals. Nell Bowen, one of the visitors, is horrified by the deplorable living conditions of the unfortunate inhabitants of this godforsaken place, better known as Bedlam.