An estranged brother and sister are reunited when they both return to their childhood home town. They try and rebuild their relationship while also dealing with their unhappy personal lives, as she considers giving up her plans to start a family and he seeks out the teacher he once had an affair with. Comedy drama, starring Bill Hader, Kristen Wiig and Luke Wilson.

Estranged twins Maggie and Milo coincidentally cheat death on the same day, prompting them to reunite and confront the reasons their lives went so wrong. As the twins' reunion reinvigorates them, they realize the key to fixing their lives may just lie in repairing their relationship.